Individuals getting methadone should have naloxone out there from the occasion of an emergency. Methadone is really a medicine which is a kind of opioid and will trigger a nasty response the place your respiration slows or most likely stops.
The concomitant use of METHADOSE with all cytochrome P450 3A4, 2B6, 2C19, 2C9 or 2D6 inhibitors could end in a rise in methadone plasma concentrations, which could bring about likely fatal respiratory depression. Additionally, discontinuation of concomitantly made use of cytochrome P450 3A4, 2B6, 2C19, or 2C9 inducers might also end in an increase
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